MAT – Medication Assisted Treatment

What is Medication Assisted Treatment (MAT)?

Medication Assisted Treatment is the use of certain medications in combination with counseling and behavioral therapies, to provide a unique “Whole-patient” approach to the treatment of Opioid and Alcohol Use Disorders. Medications used in MAT are approved by the Food and Drug Administration (FDA) and MAT programs at Embark Recovery are clinically driven and tailored to meet individual patient needs.

MAT is primarily used for the treatment of addiction to opioids like heroin and prescription pain meds that contain opiates. The medication prescribed to the patient in the MAT therapy operates to normalize brain chemistry, block the euphoric effects of alcohol and opiates, relieve psychological cravings, and normalize body functions without the negative and euphoric effects of the substance used.

Incorporating MAT in your journey can make a world of difference in the long-term. The prescribed medication operates to normalize brain chemistry, block the euphoric effects of alcohol and opioids, relieve physiological cravings, and normalize body functions without the negative and euphoric effects of the substance used.
Research shows that a combination of medication and therapy can successfully treat these disorders, and for some people who continue to struggle with addiction, MAT can help sustain recovery. MAT can also be used to prevent or reduce opioid overdose.

Medications We Use

The FDA has approved several different medications to treat alcohol and opioid use disorders MAT medications relieve the withdrawal symptoms and psychological cravings that cause chemical imbalances in the body. Medications used for MAT are evidence-based treatment options and do not just substitute one drug for another.

Acamprosate, disulfiram, and naltrexone are the most common medications used to treat alcohol use disorder. They do not provide a cure for the disorder but are most effective in people who participate in a MAT program. Learn more about the impact of alcohol misuse.
Buprenorphine, methadone, and naltrexone are used to treat opioid use disorders to short-acting opioids such as heroin, morphine, and codeine, as well as semi-synthetic opioids like oxycodone and hydrocodone.

Methadone

Methadone is a long-acting synthetic opioid agonist medication that can prevent withdrawal symptoms and reduce craving in individuals with opioid-dependence. It can also block the euphoric effects of illicit opioids. It has a long history of use in treatment of opioid dependence and is taken orally.

Buprenorphine

Buprenorphine is a synthetic opioid medication that acts as a partial agonist at opioid receptors but does not produce the euphoria and sedation caused by heroin or other opioids. Buprenorphine can reduce or eliminate withdrawal symptoms associated with opioid dependence and carries a low risk of overdose. Buprenorphine is currently available in two forms that are taken sublingually (dissolves under the tongue) and subcutaneous (injection): (1) a pure form of the substance and (2) a more commonly prescribed formulation called Suboxone, which combines buprenorphine with the substance naloxone, an antagonist (or blocker) at opioid receptors.

Naltrexone

Naltrexone is a synthetic opioid antagonist that blocks opioids from binding to the receptors and prevents the euphoric and sedating effects. Naltrexone itself has no subjective effects following detoxification and has no potential for abuse. Individuals should not use naltrexone if they are taking an opiate as they could experience sudden withdrawal symptoms. Those with low liver functioning and a history of depression should be carefully considered prior to induction.

These MAT medications are safe to use for months, years, or even a lifetime. As with any medication, consult your doctor before discontinuing use.

Naloxone is used to prevent opioid overdose by reversing the toxic effects of the overdose. According to the World Health Organization (WHO), naloxone is one of a number of medications considered essential to a functioning health care system.

Medication Assisted Treatment (MAT) Effectiveness

According to SAMHSA, in 2018, an estimated 2 million people had an opioid use disorder which includes prescription pain medication containing opiates and heroin.

MAT has proved to be clinically effective and to significantly reduce the need for inpatient detoxification services for these individuals. MAT provides a more comprehensive, individually tailored program of medication and behavioral therapy that address the needs of most patients.

The ultimate goal of MAT is full recovery, including the ability to live a self-directed life. This treatment approach has been shown to:

  • Improve patient survival
  • Increase retention in treatment
  • Decrease illicit opiate use and other criminal activity among people with substance use disorders
  • Increase patients’ ability to gain and maintain employment
  • Improve birth outcomes among women who have substance use disorders and are pregnant

Research also shows that these medications and therapies can contribute to lowering a person’s risk of contracting HIV or hepatitis C by reducing the potential for relapse. Learn more about substance misuse and how it relates to HIV, AIDS, and Viral Hepatitis.

What to Expect in the Medication Assisted Treatment (MAT) Process

First, you’ll start by meeting with our Admission team to undergo a prescreening and complete any necessary documents before progressing to the medical team. Comprised of nurses and doctors, the medical team will conduct both drug and health screenings, culminating in the creation of a tailored treatment plan for each individual. This personalized approach ensures that every aspect of the plan is specifically catered to the individual’s needs.

During this process, the medical team will discuss various medication options such as Suboxone, Vivitrol shot, or Naloxone, carefully explaining their effects and potential side effects, as well as what results can be expected. Following this, a schedule for appointments with the doctor will be established, which may vary depending on the individual’s requirements, ranging from twice a month to once a month.

The overarching objective is to facilitate the individual’s return to their normal life and routine. Through the aid of Medication-Assisted Treatment (MAT), which effectively curbs cravings and reduces the likelihood of relapse, individuals are provided with the optimal conditions for success post-treatment. This holistic approach aims to support individuals in overcoming addiction and achieving sustained recovery.

FDA Approved Products for MAT

According to the FDA website, Medication-assisted treatment (MAT) is the use of medications in combination with counseling and behavioral therapies, which is effective in the treatment of opioid use disorders (OUD) and can help some people to sustain recovery.

More must be done to facilitate treatment options and the development of therapies to address OUD as a chronic disease with long-lasting effects. This means helping more people secure MAT, which requires us to break the stigma often associated with some of the medications used to treat OUD. It also requires us to find new and more effective ways to advance the use of medical therapy for the treatment of OUD.

There are three drugs approved by the FDA for the treatment of opioid dependence: buprenorphine, methadone, and naltrexone. All three of these treatments have been demonstrated to be safe and effective in combination with counseling and psychosocial support. Everyone who seeks treatment for an OUD should be offered access to all three options as this allows providers to work with patients to select the treatment best suited to an individual’s needs.

Due to the chronic nature of OUD, the need for continuing MAT should be re‐evaluated periodically. There is no maximum recommended duration of maintenance treatment, and for some patients, treatment may continue indefinitely.

FDA-approved buprenorphine products approved for the treatment of opioid dependence include:

  • Bunavail (buprenorphine and naloxone) buccal film
  • Cassipa (buprenorphine and naloxone) sublingual film
  • Probuphine (buprenorphine) implant for subdermal administration
  • Sublocade (buprenorphine extended‐release) injection for subcutaneous use
  • Suboxone (buprenorphine and naloxone) sublingual film for sublingual or buccal use, or sublingual tablet
  • Subutex (buprenorphine) sublingual tablet
  • Zubsolv (buprenorphine and naloxone) sublingual tablets

FDA-approved methadone products approved for the treatment of opioid dependence include:

  • Dolophine (methadone hydrochloride) tablets
  • Methadose (methadone hydrochloride) oral concentrate

FDA-approved naltrexone products approved for the treatment of opioid dependence include:

  • Vivitrol (naltrexone for extended-release injectable suspension) intramuscular

SAMHSA Reference Documents

First, you’ll start by meeting with our Admission team to undergo a prescreening and complete any necessary documents before progressing to the medical team. Comprised of nurses and doctors, the medical team will conduct both drug and health screenings, culminating in the creation of a tailored treatment plan for each individual. This personalized approach ensures that every aspect of the plan is specifically catered to the individual’s needs.

During this process, the medical team will discuss various medication options such as Suboxone, Vivitrol shot, or Naloxone, carefully explaining their effects and potential side effects, as well as what results can be expected. Following this, a schedule for appointments with the doctor will be established, which may vary depending on the individual’s requirements, ranging from twice a month to once a month.

The overarching objective is to facilitate the individual’s return to their normal life and routine. Through the aid of Medication-Assisted Treatment (MAT), which effectively curbs cravings and reduces the likelihood of relapse, individuals are provided with the optimal conditions for success post-treatment. This holistic approach aims to support individuals in overcoming addiction and achieving sustained recovery.

Why Choose Embark Recovery?

Embark Recovery stands out as a premier drug and alcohol rehabilitation center in Prescott, Arizona, offering unparalleled support for Addiction Recovery since 2013. With a foundation built by individuals who have overcome addiction themselves, this state-licensed and nationally accredited facility prioritizes patient-centric treatment, providing a welcoming family atmosphere, individualized therapy programs, and evidence-based treatment plans in a serene setting.

The center’s approach extends beyond traditional therapy by preparing patients for real-world challenges, including employment readiness, financial education, and fostering healthy relationships, ensuring a holistic recovery journey.

Embark’s clinical team, all holding master’s level education and extensive experience in substance abuse and behavioral health treatment, along with strong partnerships with Residential Services Providers, ensures a safe, nurturing environment. This commitment to excellence is further enhanced by regular family involvement, weekly clinical psychiatrist visits, and voluntary participation in outdoor activities, promoting a positive peer culture and a comprehensive path to recovery.

Understanding the financial hurdles of treatment, Embark Recovery offers 24/7 admissions support to navigate these challenges, truly setting an industry standard for care and service.